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Science to discover the cellular mechanism that drives plants to work for parasites



Science to discover the cellular mechanism that drives plants to work for parasites

Many parasites capture the cellular mechanism of their hosts and manipulate them to suit their life and needs.

These parasites force their plant hosts to provide adequate housing for their needs and abandon reproduction, but scientists do not know much about the molecular and mechanical details of this process.

Phytoplasma bacteria are characterized by the ability to reproduce the growth of their host plants (contact sites)

Abnormal growth

And recently, revealed Research study It was published in the September 17 issue of Cell magazine about a new mechanism used by parasitic bacteria to slow the aging process in plants. This will pave the way for the protection of disease-prone crops.

And step For press release Published by the John Innes Center in the United Kingdom, commenting on the study; Researchers have identified a biomolecule produced by phytoplasma bacteria to manipulate plant growth; The production of this protein within the plant disrupts important regulatory growth factors, resulting in abnormal plant growth.

Phytoplasma belongs to the group of bacterial microorganisms, which are characterized by the ability to reproduce the growth of their host plants, and this group of bacteria often causes an event in trees called “witch brooms”, which have a large number of tree branches. Grow close to each other. Some.

These dense gatherings of branches are the result of the plant stopping its reproduction and becoming inactive. In addition, phytoplasma bacteria cause crop-destroying diseases such as aster yellow, resulting in significant loss of leaf and grain crops.

SAP 05 makes the most of a plant’s cellular machinery through its host (Uric Alert – John Innes Center).

Cellular manipulation

“Phytoplasma is a prime example of how genes can spread beyond organisms and affect the environment,” said Saskia Hoganhout (head of the study).

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“Our findings shed light on the molecular mechanism that causes these phenotypes, which may help find solutions to key problems related to food production,” Hooganhout added. The team’s findings show that a bacterial protein called SAP05 makes extensive use of the plant’s cellular machinery for its host.

It is known that there is a cellular machine called a “proteasome” – the function of breaking down proteins that are damaged by plant cells or are no longer needed.

However, the “sub05” protein handles this cellular mechanism, which must dispose of the proteins needed to regulate growth and development by sending them to the “proteasome” without being naturally removed by the cell.

Therefore, the lack of proteins that regulate plant growth and development leads to reprocessing of plant growth in favor of bacteria; It slows down the aging process by growing many buds and plant tissues.

Substitution of two amino acids inhibits abnormal plant growth (contact sites)

A promising strategy

The team conducted several genetic and biological experiments on “Mouse Ear Cress” (Arabidopsis taliana) plants, which helped to understand the comprehensive role of the “sub05” protein. At the same time “proteome”.

However, plant proteins necessary for growth and development bind to SAP 05, which is similar to some proteins found in animal cells; The team therefore studied the interaction of sub05 protein with proteins found in insects responsible for the transmission of bacteria from one plant to another. However, animal proteins were found to be structurally different from their plant counterparts, so they did not bind to sub05 protein.

The previous result helped identify two amino acids found in animal proteomes. The team observed that if these two amino acids were converted in the same way as the insects in the plant, the proteins that control growth and development would not bind to the “sub05” protein, and would not be abnormally removed. Inhibits the abnormal growth of the plant, and then the so-called “broom of witchcraft” form does not appear.

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Ministry of Health reveals number of coronavirus infections within a week



Ministry of Health reveals number of coronavirus infections within a week

Today, Friday, in its weekly bulletin, the Ministry of Health and Social Security (Covid-19) announced that a total of 205 new infections have been recorded, while no deaths have been recorded.

In its weekly bulletin of (Covid-19) results covering the period from September 16 to September 22, 2023, the ministry highlighted that the number of people vaccinated reached 24 million and the number of people who received the first dose reached 924 thousand 167. The number of people vaccinated with the second dose increased by 23 million to 426 thousand 39, and a total of 6 million 886 thousand 744 received the third dose of antiviral vaccine to 61 thousand 121. Those who received the fourth level of reminiscence.

The ministry added that since the first case was reported on March 2, 2020, the weekly “positive, new infections with the virus brought the number of confirmed infections in the Kingdom to one million, 276 thousand 635”. Rate” is approximately 5.6 percent.

Casablanca-Settat (62), Rabat-Salé-Kenitra (79), Fes-Meknes (12), Souze-Massa (18), Beni Mellal-Kenifra (10) and The. Orient Region (2). , Marrakesh-Safi (20), Dra-Tafilalet (1), and Tangier-Tetouan-Al Hoceima (1).

With no deaths reported in the past week, the total number of deaths is estimated at 16,297 (a general mortality index of 1.3 percent).

The total number of active cases reached 250 and one active case was registered during the same period.

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Solidarity launches campaign for early detection of cervical cancer and reproductive health



Solidarity launches campaign for early detection of cervical cancer and reproductive health

By Medhat Wahba

Friday, September 22, 2023 01:21 PM

Social Unity Minister Dr. Nevin Al-Kabaj began his journey to Alexandria Governorate today, Friday, to launch the campaign.A journey of a thousand kilometersBy opening the “Reproductive Health and Early Detection of Cervical Cancer” clinic, the focus is on early detection of cervical cancer and reproductive health..

The Minister of Social Unity confirmed that the “Thousand Kilometer Journey” is scheduled to start today from Alexandria Governorate and continue for two days, from there to 9 Governorates of Beni Souf, Minya, Assiut and Sohaq. , Qana, Luxor and Aswan for two days in each governorate, and finally its activities will end in Cairo Governorate on January 5th and 6th next year..

Al-Kabbaj added that the trip targets three activities, the first of which is related to awareness, where social pioneers in those governorates will be trained to improve awareness and their medical awareness. The second part of the trip is related to training the medical staff of the clinics. In these governorates, “Reproductive Health and Early Detection of Cervical Cancer” has been prepared, where doctors and nurses will be trained on the use of various family planning methods. and the use of the cervical speculum to ensure the delivery of clinical care with high efficiency through workshops and clinical conferences..

The third part of the campaign is economic empowerment, as a bazaar will be established in each governorate where the campaign travels with the aim of promoting their products to women producers and small enterprises..

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Scientists are tracking a tree in Brazil that was thought to have died out 185 years ago



Scientists are tracking a tree in Brazil that was thought to have died out 185 years ago

I retired at 100… A centenarian talks about the importance of “being busy at work” to live a long life.

Madeleine Balto recently retired at the age of 100, having worked for more than 80 years – from the age of 18 to 99. According to a CNBC report, Balto believes work has contributed to his longevity.

Balto says of his previous job: “It kept me busy, and I enjoyed the work… As for retirement, I don’t really like it.”

The Balto family started an electric sign manufacturing business in Chicago, with Madeline responsible for office work. She often interacted with customers and it was her favorite job.

She said: “I loved interacting with people… and I was the only one in the office doing all the office work, so it was fun.” “I loved going to work.”

An 85-year-old Harvard University study found that positive relationships make people happier and help them live longer. For this reason, it is not surprising that Balto places a strong emphasis on the importance of family and friends.

Assistant Professor of Medicine and Genetics and Director of Human Lifespan Studies at the Albert Einstein Institute for Aging Research, Dr. Sophia Melman says. College of Medicine.

At 100, Balto maintains his sense of community by going out to dinner with his sons and attending family events. Finally attended a wedding earlier this month.

She also likes going to the Dunkin’ Donuts branch every Sunday with her son to meet friends. “I look forward to it every week,” he says.

Balto affirms that she is lucky; Because she has some friends of the same age who often come to her house for lunch.

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She added: “They always invite me over and come over for lunch on Wednesdays at 12pm… we have fun together… without your friends, where are you, right?”

While maintaining healthy relationships is an important factor in living longer, there are other factors that contributed to Balto’s longevity.

First, Mellman says, “In general, women’s life expectancy is longer than men’s…and we believe that genetics also has a significant relationship with longevity.”

In fact, Balto’s older sister lived to be 103 years old. “But she and I are the only ones who lived over 100 years,” she says, referring to her parents, who died at 84, and her sisters, who didn’t live very long.

I grew up on a vegetarian diet

Aiming to stay active, Balto says, “I’m still getting around better. I can walk up the stairs. I have energy; “so I’m in pretty good shape.”

She also tries to eat as healthy as possible, something that started in her childhood, she explains: “When I was a child, there were seven children in the family, and my father was building a big garden, so we lived mostly. On vegetables. “There wasn’t a lot of meat, we couldn’t afford meat.”

“I think that’s probably why I eat healthier,” she adds. Don’t eat fast food now.

Millman says centenarians are generally more confident, and Balto fits that description. He says it’s unclear whether centenarians are always positive, or whether they develop their positive outlook as they age.

Balto says she doesn’t feel too nervous; Because “everything can be solved.” She continues: “I’m very lucky; As I am 100 years old, I am in good health… I cannot complain about my health. “I’m walking, talking, no pain.”

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