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A living, thread-like worm in an Australian woman’s brain



A living, thread-like worm in an Australian woman’s brain

The Royal Commission for AlUla Governorate launched the second Master Plan for Urban Development for Central and South AlUla, aimed at improving living standards and stimulating economic growth and urban development within the framework of comprehensive sustainable development set out in the “AlUla Vision”. In line with Saudi Vision 2030, making the city a unique place of stability and work.

Extensive urban development

The Commission announced the strategic direction of the program bearing the slogan “Towards a Prosperous Society” and aimed at urban development, urban development and development of residential land uses, improving services and facilities, achieving public health goals, improving sustainable mobility experience and others.

Speaking at the launch, Amr Madani, CEO of the Royal Commission for AlUla said: “The launch of the Towards a Prosperous Society project is a continuation of AlUla’s comprehensive development journey and reaffirms the Commission’s commitment to improving neighborhoods and residential communities. To achieve new prosperity and improve the quality of life in South and Central AlUla.”

The Commission reaffirmed its commitment to promoting comprehensive sustainable development, promoting the urban development of the governorate and preparing it through a system of programs and initiatives to achieve “people before place” development as a fundamental mechanism. Vision by presenting architectural models and designs inspired by traditional architectural styles in AlUla.

The plan establishes what will make Al-Ula a better place to live and work (Royal Commission for Al-Ula).

Improving quality of life

The Master Plan “Towards a Prosperous Community” is a comprehensive development plan focused on improving the quality of life of the people and residents of AlUla. It aims to achieve a comprehensive and sustainable transformation of the urban area in AlUla. It will work. Increase economic opportunities, sustain population growth, and provide high-quality education, health, and transportation services.

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The project also includes creating public spaces to enrich the lives of AlUla’s people and residents and providing a number of transportation solutions that allow easy movement throughout AlUla while promoting a healthy and active lifestyle. Allowing a deeper connection with the surrounding environment. This will enhance the achievement of the project’s objectives of making Al-Ula a promising place to live and work.

The plan includes improving infrastructure and the built environment and enhancing the quality of services provided (Royal Commission for Alula).

Completing the comprehensive development process

The second master plan represents a roadmap for the development of the central and southern parts of AlUla, which will complete a comprehensive development phase announced in 2021, introducing a design vision of “a journey through time”. and the restoration of the main archaeological site at Al-Ula. Both projects aim to make the city a leading global destination for art, heritage, culture and nature, and a great place to live and work.

The project includes the provision of elements of activities aimed at improving the infrastructure and built environment and raising the quality of services provided, as well as raising the quality of health services, raising the quality of recreational activities and improving comprehensive sustainability in residential areas. As well as providing various facilities, as well as several transport routes, with the coordination of “Wadi Al-Qura” with the neighboring areas of the governorate.

The project will bring together man and nature in perfect harmony (Royal Commission for Al-Ulaah).

Environmental and social friendly project

The “Towards a Prosperous Society” plan is based on achieving economic development, taking care of cultural and natural heritage, “humanizing the city” and providing an urban experience with its life services in various neighborhoods and locations. The second phase of the basic plan is based on the foundation of the Al Ullah Sustainability Charter, which aims to implement a circular carbon economy and achieve full carbon neutrality in Al Ullah Governorate.

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The project will create innovative infrastructure that will provide the necessities of life in neighborhoods characterized by urban style and integrated services. It will create a harmonious environment that connects people with nature and build on the ancient heritage of the governorate. It will also provide neighborhoods with many key services and amenities such as green spaces, playgrounds and parks.

The project will achieve carbon neutrality by 2035 (Royal Commission for Al-Ulah).

It is worth noting that Al-Ula has many historical and social benefits, as it contains many historical monuments dating back more than 200 thousand years, and it contains the ancient Nabatean city of “Al-Hijr”. Considered Saudi Arabia’s first UNESCO World Heritage Site, the ancient capitals of two kingdoms include the ancient sites of Lihyan and Dadan in addition to the “Old AlUla” considered a resting place for pilgrims since 1100 AD.

The launch of the project Towards a Prosperous Community is a continuation of the comprehensive development journey in AlUla and a confirmation of the Authority’s commitment to the development of neighborhoods and residential communities in South and Central AlUla.

Amr Madani – CEO of the Royal Commission for Al Ullah Governorate

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Finding the genetic causes of a rare cancer affecting the kidney



Finding the genetic causes of a rare cancer affecting the kidney

An international team led by researchers at the British Wellcome Sanger Institute has revealed a new drug target that could act as an alternative treatment for kidney cancer if doctors don’t recommend surgery. According to the results of a study published in the journal Nature Communications (Monday), this rare cancerous form of kidney tumor is called Renin tumor, and its complete genetic code has been understood for the first time.

Reninoma is one of the rarest cancers in humans, with only about 100 cases reported worldwide. Although it can usually be treated with surgery, it can cause severe high blood pressure and develop into malignant tumors that can spread.

There are still no medical treatments for kidney tumors, as treatment management only involves surgery. Before the results of the latest study came out, it was not known what genetic error caused these types of tumors.

Reninoma is one of the rarest cancerous tumors in humans (Public Domain).

According to the study’s co-principal investigator, Dr. Sam Bagadi, Wellcome Senior Research Fellow at the Wellcome Sanger Institute: “The significance of our results is that we have succeeded in discovering the essence of this type of tumor. Based on the fact that it is so rare, there have been no previous studies on it.

He added to Asharq Al-Awsat: “Not only have we been able to understand the genetic code of a kidney tumor, but we have also shown that drugs can counteract what triggers it, and this may be important for patients whose tumors cannot be removed. through surgery.”

Researchers have identified a specific error in the genetic code of a known cancer gene called NOTCH1, which is behind the development of this rare cancer.

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“This is the first time we have identified the causes of kidney tumors, and we believe our work will continue to pave the way for new treatments,” said lead study author Taryn Trescher at the Wellcome Sanger Institute.

The team has already studied two cancer samples, one from a young adult and the other from a child, using advanced genetic techniques. Their findings suggest that existing drugs that actually target this gene could be used as a potential solution for treating kidney tumors in patients for whom surgery is not a viable option.

Dr Tansina Chowdhury, lead researcher on the study at Great Ormond Street Hospital in the UK, explained: “Rare forms of kidney cancer known as renal tumors do not respond to traditional anti-cancer treatments. “Currently the only known treatment is surgery.” She added: “There is a specific, well-known gene that drives this rare cancer. Our study shows that the studied gene has “If we use drugs that are already known to affect this gene, we can deal with it without the need for invasive medical technology like surgery.”

Here Bahjati said: “Rare cancers are a huge challenge for research and analysis. Patients with other types of tumors may not benefit from them. “But here is a powerful example of cutting-edge science that is changing our understanding of an extremely rare type of tumor: a discovery that could have immediate clinical benefits for patients.” He added: “We will continue to study these extremely rare tumors to understand their genetic code, which we hope will reveal more new therapeutic approaches.”

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Climate change: Saudi Arabia warns against rush to abandon traditional fuels – Financial Times



Climate change: Saudi Arabia warns against rush to abandon traditional fuels – Financial Times

image source, Good pictures

We begin our tour of British newspapers with Amy Williams in New York and Miles McCormick in Calgary at the Financial Times on what they describe as deep tensions and divisions over the oil and gas industry’s role in combating climate change. Recent events in New York, US and Calgary, Canada this week cast doubt on the likelihood of an agreement at the upcoming United Nations COP28 conference.

According to the article, when world leaders and senior officials meet in New York in ten weeks ahead of the United Nations’ COP28 climate summit, there is a deep divide between those who support and those who urge the expansion of fossil fuel use. Stopping all forms of growth and expansion is critical to achieving stability in the world.

In December, the UN The authors quoted Dan Jorgensen, Denmark’s minister for development cooperation and global climate policy, who is leading discussions on new climate targets that could be agreed at the climate change conference COP28, as saying: “Countries agree that we must move. Move forward on this issue.” “But the bad news is that we’re far from reaching an agreement. We need to address the larger problem of burning fossil fuels.”

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What are the most common symptoms of breast cancer in men?



What are the most common symptoms of breast cancer in men?

Breast cancer is a disease that affects women, especially with a high number of infections, but in fact it affects men as well, and many believe that it leads to death among them.

she explained NHS The NHS in England says that 85 men die each year in Britain from breast cancer, and that the malignancy affects around 400 men annually.

The charity Breast Cancer Now also reports that “at least one person is diagnosed with the disease every day”.

According to the website “Mayo ClinicMedically, male breast cancer is “a rare cancer that begins with the growth of cells in the breast tissue of men.”

Breast cancer cells disrupt the immune system

Australian researchers announced Monday that breast cancer cells have powerfully destroyed the body’s immune system, allowing the disease to invade patients’ bones.

“Breast cancer in men usually affects older people, but it can occur at any age,” he pointed out.

Those diagnosed with “male breast cancer” at an early stage have a good chance of recovery.

What are the symptoms?

The symptoms of this disease are as follows:

A painless lump or thickening of breast tissue and changes in the skin of the breast, such as sagging, wrinkling, redness or peeling.
Changes in the nipples, such as redness or peeling, or one of the nipples turning inward.

The causes of these malignant tumors are still unclear, but doctors define “male breast cancer” as occurring when “some breast cells divide faster than healthy cells.”

Accumulated cells form a tumor, which can spread (metastasize) to nearby tissues, lymph nodes, or other parts of the body.

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According to the website “Web MedicineThe disease can be diagnosed through a clinical examination, which is done by feeling the chest area of ​​the person in search of any tumors or changes in the chest tissue, and the doctor evaluates the size, structure and depth of the tumors present.

It can be diagnosed with radiographic imaging such as X-rays or ultrasound to create clear images of the breast tissue.

Only a biopsy is used to “confirm” a diagnosis of breast cancer in men. This is done by taking a sample of the tumor tissue and examining it to confirm whether the tumor is cancerous or benign.

Treatment usually involves surgery to remove as much of the visible tumor as possible, along with some of the surrounding healthy tissue.

Other treatments such as chemotherapy and radiotherapy may be recommended depending on the condition.

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