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Harvard researchers have developed a data storage approach based on the composition of fluorescent dyes printed on epoxy surfaces with small dots. The composition of the dyes at each location encodes information read through a fluorescence microscope.
Optical drives, USB sticks and magnetic hard drives can only store digital information for a few decades, and while their maintenance power is high, these methods are not ideal for storing data at home. كبدائل ، ، ولا سيما DNA data storage. However, these methods present their own challenges, including higher package costs and slower reading and writing rates.
Now, Harvard scientists have figured out how to use fluorescent dyes because data storage is cheap and fast. New paper Published in ACS Central Science Journal. Researchers saved a 19th-century physicist and tested their method Michael FaradayBasic documents on electromagnetism and chemistry and Faraday’s JPEG image.
“This method can access archive data storage at low cost.” Co-author Amit A. Nagercoil. Said, A graduate of George Whiteside’s Harvard Laboratory. “[It] Provides access to long-term data storage using current business technologies: inkjet printing and fluorescence microscope. Nagercoil is now working with a startup that wants to commercialize the system.
Chris Snape / Harvard staff
There are good reasons for the idea of using DNA to store data. As we have As mentioned earlierThere are four chemical building blocks in DNA – adenine (A), thymine (D), guanine (G) and cytosine (C) – which make up a type of code. Data can be stored in DNA by converting data from binary code to base code 4 and assigning it to one of four characters. DNA has a higher data density than traditional storage systems. Only one gram Can be represented Nearly one billion terabytes (1 jet byte) of data. It is a powerful medium: stored data can be stored for long periods of time, decades or even centuries.
The storage of DNA data has made significant improvements in recent years, bringing some innovative twists and turns. For example, two years ago, Stanford scientists succeed He created a 3D printed copy of the Stanford rabbit – a common experimental model in 3D computer graphics – that stored the printing instructions for breeding the rabbit. The rabbit contains about 100 kilobytes of data, thanks to the inclusion of DNA-containing nanoparticles in the 3D-printed plastic.
But the use of DNA presents difficult challenges. For example, the storage and retrieval of DNA data usually takes a long time, taking into account all the necessary sequences. Our ability to integrate DNA is still a long way off from becoming a practical way of storing data. Therefore, other scientists have explored the possibility of using non-biological polymers to store molecular data, by decoding (or reading) the information stored by sorting the polymers using tandem mass spectrometry. However, the production and refining of synthetic polymers is an expensive, complex and time consuming process.
Chris Snape / Harvard staff
In 2019, WhiteSite Lab Show Success Save information in a mix of commercially available information Some peptides On a metal surface, without the need for long and expensive assembly techniques. The laboratory used a mass spectrometer to mark the molecules of the molecules in order to study the stored information. But there are still some issues, including that the information is distorted while reading. In addition, the reading process was slow (10 bits per second) and reducing the size was difficult because reducing the size of the laser point increased the noise in the data.
Ark city Cow. I decided to study molecules that could be visually differentiated rather than molecular weight. In particular, they selected seven commercially available fluorescent dyes in different colors. To “record” the information, the team used an inkjet printer to place solutions of mixed fluorescent dyes on the epoxy substrate containing some reactive amino groups. The subsequent reaction creates stable amide bonds, effectively locking the information.
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