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Ilya Mitsinikov, a Russian Nobel Prize-winning scientist and one of the founders of immunology, turned his scientific career and scientific community upside down in 1895 when he focused on his studies in old age rather than immunity.
Renowned Russian scientist Ilya Mitsinikov was inspired by the role that intestinal bacteria play in human health and diseases, and suggested that people in the eastern parts of Europe live longer because they ate a lot of fermented foods containing lactic acid bacteria.
Scientists have long disregarded the theory that intestinal microbes combine with healthy aging, although it was common at the time, and until this theory came to the fore again, the importance of this bacterium, known as intestinal microbiota, appeared in controlling health and disease in humans (Diet # 1 to enhance the most important process in the body responsible for cell repair and energy)
Evidence that the composition of microorganisms changes with age has been accumulating for nearly a decade. In 2012, research by Cork scientists at Cork University showed that diversity in microorganisms is related to human health, life, vulnerability and aging.
Accurate study of the research of the Russian scientist
Cow The prestigious science journal “Scientolard” was reviewed in 2017 by scientistsPutting the ideas of the Russian scientist Magnikov in the background of the study of brain aging, the results show that aging changes in these bacteria and the immune system, and the decline of these bacteria is associated with cognitive decline and anxiety.
But in a subsequent study, scientists focused on the link between a microbial-targeted diet enriched with prebiotic insulin (a key substance that promotes beneficial bacteria in the gut) and showed that this intervention reduces the effects of aging on middle-aged mice. However, it is not clear whether germs slow brain aging.
But new A study conducted by a team of scientists confirmed the taking of the microbe As they are transplanted into younger mice and older mice, many of the effects of aging associated with learning, memory, and immune impairment will be reversed. The scientists also showed that the process of transferring the microbes extracted from the feces of young mice to older mice led to a significant improvement in the brain processes of the latter and delayed the signs of aging. Read more: (Scientifically proven: One pear a day excludes you from beauty products and salons)
How did a Russian scientist combine aging with immunity a century ago?
It is associated with increased incidence of senile inflammation in all body systems, including the brain. Immune processes play a major role in brain aging, focusing on the role of a particular immune cell, the microglia.
Paradoxically, these are the same type of cells that Russian scientist Magnikov saw in his microscope and light through other tissues in the late 19th century. But scientists now know that the activation of these cells is constantly controlled by the gut microbiome.
Scientists have finally discovered that the chemicals that contribute to learning and memory in a specific area of the brain (hippocampus) are similar to those found in young mice after microbial transplantation. Results show that microbes are important for brain health in old age.
The magazine wondered if Mitchnikov’s transition from immunology to old age was a prelude to understanding the maturity of maturity? In fact, according to the article, the comparative contribution of immune changes found in mice receiving microbiota to overall regenerative effects is worthy of further study.
Can it be used for humans … Did the Russian scientist talk about it?
These studies indicate that in the future the focus will be on nutritional therapies targeting germs or bacteria-based therapies that promote optimal gut health and immunity to keep the brain young and healthy. “Strategies like these are more of an acceptable life elixir than a process of extracting bacteria from feces.”
Magniko’s general principles seem right: “Protecting your gut microbiome may be the secret of youth. With advances in health care, longevity has increased significantly,” which confirms his hypothesis.
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